000			02015nam a22002657i 4500
005			20250805140810.0
008			250805s2022 us a|||fr|||| 00| 0 eng d
020			_a9781639273102
040			_aEG-GaU‬‬ _cEG-GaU‬‬ _dEG-GaU‬‬ _erda
082	0	4	_223 _a616.8 _bp.e.n
100	1		_aPoole, Elena. _eauthor. _961382
245	1	0	_aNeurodegeneration : _bAdvances in Neuroscience / _cElena Poole.
250			_aFirst edition.
264		1	_aNew York : _bAmerican Medical Publishers, _c2022
300			_a227 pages : _bIllustrations ; _c28 cm
336			_2rdacontent _atext _btxt
337			_2rdamedia _aunmediated _bn
338			_2rdacarrier _avolume _bnc
520			_aNeurodegeneration is the gradual loss of neurons, and neuronal structure and function. This is the cause of neurodegenerative diseases, such as Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, etc. Research in neurodegeneration suggests that there exists several similarities between these disorders such as induced cell death and atypical protein assemblies. DNA damage accumulation has been proposed to be the causative link between neurodegeneration and aging. Several mechanisms have been implicated in the occurrence and progression of neurodegeneration, such as protein misfolding, programmed cell death, genetic mutations, various intracellular mechanisms, etc. Protein degradation is a therapeutic option for preventing the synthesis and degradation of irregular proteins that are formed in neurodegenerative disease. This book is a compilation of chapters that discuss the most vital concepts and emerging trends in neurodegeneration. Different approaches, evaluations and advanced studies have been included herein. The extensive content of this book provides with a thorough understanding of the subject.
650		0	_aNeurodegenerative diseases. _961278
650		0	_aNeurodegeneration. _961383
650		0	_aNeuroscience.
942			_2ddc _cBK
999			_c11446 _d11446