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008 141202s2015 gw |||| o |||| 0|eng
010 _a 2019748635
020 _a9783030308445
020 _a9783662440063
024 7 _a10.1007/978-3-662-44006-3
_2doi
035 _a(DE-He213)978-3-662-44006-3
040 _aDLC
_beng
_epn
_erda
_cDLC
072 7 _aMED045000
_2bisacsh
072 7 _aMJ
_2bicssc
072 7 _aMJ
_2thema
082 0 4 _a616
_223
245 0 0 _aCancer Immunology :
_bA Translational Medicine Context /
_cedited by Nima Rezaei.
250 _a1st ed. 2015.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg :
_bImprint: Springer,
_c2015.
300 _aXLVII, 597 pages :
_b269 illustrations, 246 illustrations in color.;
_c24 cm
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aIntroduction on cancer immunology and immunotherapy -- Inflammatory and innate immune cells in cancer microenvironment and progression -- Role of innate immunity in cancers and antitumor response -- Role of B cells in anti tumor response -- The role of exhaustion in tumor-induced T cell dysfunction in patients with cancer -- Regulatory T cells and Th17 cells in the immunosuppressive tumor network -- Role of cytokines in tumor immunity and immune tolerance to cancers -- Role of chemokines and chemokine receptors in cancers -- The role of Fas and Fas-ligand in cancers -- MHC class I molecules and cancer progression: Lessons learned from preclinical tumor models -- Role of plasmacytoid dendritic cells in cancer -- Cancer immunoediting: immunosurveillance, immuneequilibrium, and immune escape -- Apoptosis, autophagy and necroptosis in Cancer -- Prognostic value of innate and adaptive immunity in cancers -- Epigenetics and Micro RNAs in cancers -- Immunogenetics of cancers -- Immunodeficiencies and cancers -- Immunosenescence and cancers -- Nutrition, immunity and cancers -- Allergies and cancers -- Cancer immunology of transmissible cancers -- Systems biology and systems immunology of cancer -- Principles of immunological diagnostic tests for cancers -- Flow cytometry in cancer immunotherapy: applications, analysis, quality control and future -- Immunohistochemistry of cancers -- Immunology and immunotherapy of graft versus host disease.
520 _aCancer Immunology is intended as an up-to-date, clinically relevant review of cancer immunology and immunotherapy. The rapid flow of studies in the field of cancer immunology during the last decade has increased our understanding of the interactions between the immune system and cancerous cells. In particular, it is now well known that such interactions result in the induction of epigenetic changes in cancerous cells and the selection of less immunogenic clones as well as alterations in immune responses. Understanding the cross-talk between nascent transformed cells and cells of the immune system has led to the development of combinatorial immunotherapeutic strategies to combat cancer. This volume is focused on interactions between cancerous cells and various components of the innate and adaptive immune system are fully described. Notably, the principal focus is very much on clinical aspects, the aim being to educate clinicians on the clinical implications of the most recent findings and novel developments in the field. This is to be hoped that this translational book will be comprehensible, cogent and of special value for researchers and clinicians who wish to extend their knowledge on cancer immunology.
588 _aDescription based on publisher-supplied MARC data.
650 0 _aHematology.
_9420
650 0 _aImmunology.
650 0 _aInternal medicine.
650 0 _aOncology.
_923622
650 1 4 _aInternal Medicine.
_0https://scigraph.springernature.com/ontologies/product-market-codes/H33002
650 2 4 _aHematology.
_0https://scigraph.springernature.com/ontologies/product-market-codes/H3307X
_9420
650 2 4 _aImmunology.
_0https://scigraph.springernature.com/ontologies/product-market-codes/B14000
_925017
650 2 4 _aOncology.
_0https://scigraph.springernature.com/ontologies/product-market-codes/H33160
_925018
700 1 _aRezaei, Nima.
_eeditor.
_923624
776 0 8 _iPrint version:
_tCancer immunology : a translational medicine context
_z9783662440056
_w(DLC) 2014952677
776 0 8 _iPrinted edition:
_z9783662440056
776 0 8 _iPrinted edition:
_z9783662440070
776 0 8 _iPrinted edition:
_z9783662512524
856 4 1 _uhttps://library.gu.edu.eg/cgi-bin/koha/opac-retrieve-file.pl?id=c09b622b3f34dc83cefff20f38cf0420
_zGet the E-Book
906 _a0
_bibc
_corigres
_du
_encip
_f20
_gy-gencatlg
942 _2ddc
_cBK
999 _c40
_d40