Includes bibliographical references and index.

Searching for memory in the brain: CONFRONTING THE COLLUSION OF CELLS AND SYSTEMS, J.L. McGaugh<BR>One Hundred and Fifty Years of Controversy<BR>The Great Debate: What is Learned - Knowledge or Responses?<BR>Brain Systems and Forms of Memory <BR>Brain Systems and Memory Functions.<BR>Cells and Systems<BR>Two Centuries of Progress in Research on Brain and Memory<BR>References<BR><BR>LONG-TERM POTENTIATION AND DEPRESSION AS PUTATIVE MECHANISMS FOR MEMORY FORMATION, M.L. Escobar and B. Derrick<BR>Introduction<BR>Long-Lasting Forms of Synaptic Modification: A Methodological Approach<BR>LTP and LTD: Triggering, Expression, and Maintenance Mechanisms<BR>Persistent Synaptic Plasticity: A Metaplastic Point of View<BR>The Role of Activity-Dependent Synaptic Plasticity in Brain Function<BR>Substrates of LTP and LTD - Structural Plasticity<BR>Neurotrophins and Synaptic Plasticity<BR>Experience-Dependent Modifications - Is LTP Involved in Learning and Memory?<BR>Outstanding Questions and New Directions<BR><BR>MOLECULAR MECHANISMS OF SYNAPTIC PLASTICITY UNDERLYING LONG-TERM MEMORY FORMATION, V. Ramirez-Amaya<BR>Early Signals. <BR>Ca2+ and its transducer<BR>Immediate early genes.<BR>Trophic Factors.<BR>Conclusions<BR><BR>MODIFICATION OF BRAIN CIRCUITS THROUGH EXPERIENCE, M.R. Rosenzweig<BR>Brain Plasticity Discovered through Serendipity <BR>Unexpected Discovery of Brain Plasticity<BR>Cerebral Effects of Experience Occur in All Species Tested <BR>Enriched Environments and the Brain<BR>Neurochemical Cascades Underlie Modification of Neural Circuits <BR>Acknowledgments<BR>References<BR><BR>PRESYNAPTIC STRUCTURAL PLASTICITY AND LONG-LASTING MEMORY: FOCUS ON THE LEARNING-INDUCED REDISTRIBUTION OF HIPPOCAMPAL MOSSY FIBERS, J.L. Rekart, M.R. Holahan, and A. Routtenberg<BR>Learning And Structural Plasticity<BR>Hippocampal Granule Cell Axon Terminals And Learning<BR>Mechanisms Of Presynaptic Structural Plasticity<BR>The Presynaptic Disparity: Anti-Boutonism or a Biological Reality?<BR><BR>ELECTROPHYSIOLOGICAL REPRESENTATION OF TASTE MEMORY, T. Yamamoto and Y. Yasoshima<BR>Introduction<BR>CTA paradigm<BR>Enhanced response to the CS<BR>Alteration of responses reflecting hedonic shift<BR>CS-US association<BR>Importance of amygdala in CTA formation<BR>Involvement of reward system<BR>Summary<BR><BR>CHANGES IN NEUROTRANSMITTERS EXTRACELLULAR LEVELS DURING MEMORY FORMATION, M.I. Miranda<BR>Introduction<BR>The Free Moving Microdialysis Technique<BR>Acetylcholine Release During Motor Activity, Attention, and Novelty <BR>Novelty and Other Neurotransmitter Release<BR>Lesions and Blockade of Cholinergic Activity During Memory Formation<BR>Acetylcholine and Long Term Memory Tasks<BR>Noradrenaline Release During Memory Formation<BR>Glutamate and GABA Release During Memory Formation<BR>Conclusions<BR><BR>REVERSIBLE BRAIN INACTIVATION OF BRAIN CIRCUITS IN LEARNING AND MEMORY RESEARCH, M. Gallo<BR>Introduction<BR>The Brain Lesion Approach and the Dynamic Nature of Learning and Memory Systems<BR>Reversible Inactivation Techniques<BR>Learning Behavioral Models and Reversible Inactivation Techniques<BR>Dissociating Independent Learning and Memory Processes<BR>Summary<BR><BR>ENHANCED LEARNING PROTECTS THE BRAIN AGAINST THE EFFECTS OF AMNESIC TREATMENTS, R.A. Prado-Alcalá, R. Salado-Castillo, C. Quiroz, M.E. Garín-Aguilar, A. Díaz-Trujillo, S. Rivas-Arancibia, and G.L. Quirarte<BR>Introduction <BR>Protective Effect of Enhanced Training<BR>Two Models<BR>Conclusions<BR>References<BR><BR>STUDIES ON SHORT-TERM AVOIDANCE MEMORY, M. Cammarota, L.R.M. Bevilaqua, J.H. Medina, I. Izquierdo<BR>Summary<BR>Introduction<BR>STM and LTM: Parallel or Sequential?<BR>The Role of the Hippocampus in Avoidance STM and LTM<BR>The Role of the Entorhinal Cortex in Avoidance STM and LTM<BR>The Role of Other Cortical Areas and of the Amygdala in IA's Memory <BR>Neurobiological Separation of Short and Long Term Avoidance Memory<BR>STM and LTM are Behaviorally Different<BR>The Biochemistry of Short Term Memory<BR>Pharmacological Analysis of IA's Working Memory<BR>Conclusions<BR>References<BR><BR>MEMORY RECONSOLIDATION OR UPDATING CONSOLIDATION? C.J. Rodriguez-Ortiz and F. Bermudez-Rattoni<BR>Abstract<BR>The Consolidation Hypothesis<BR>The Reconsolidation Era<BR>On the Restraints of the Reconsolidation Hypothesis<BR>Are Consolidation and Reconsolidation the Same Process?<BR>The Reconsolidation Hypothesis Reconsidered: The Updating <BR>Consolidation Proposal<BR>Acknowledgments<BR>References<BR><BR>MEMORY IMPAIRMENTS ASSOCIATED WITH STRESS AND AGING, C. Sandi<BR>The Concept Of Stress<BR>The Physiological Stress Response<BR>Stress And Memory Function <BR>Acute Stress And Memory Impairment <BR>Neurobiological Mechanisms Involved In The Acute Effects Of Stress On Memory<BR>Impairing Effects Of Chronic Stress On Cognitive Function<BR>Neurobiological Mechanisms Involved In The Deleterious Effects Of Chronic Stress On Brain And Behavior<BR>Stress And Aging<BR>Aging<BR>Memory Deficits In The Aging Human Population<BR> Neurobiological Mechanisms Associated To Age-Related Cognitive Decline In Humans<BR>Memory Deficits In Aged Rodents<BR>Aging And Structural And Functional Plasticity<BR>Conclusions<BR>References<BR><BR>ADRENAL STRESS HORMONES AND ENHANCED MEMORY FOR EMOTIONALLY AROUSING EXPERIENCES, C.K. McIntyre and B. Roozendaal<BR>Introduction<BR>Stress Hormone Effects on Memory Consolidation<BR>Stress Hormones Selectively Enhance Memory Consolidation of Emotionally Arousing Experiences<BR>Involvement of the Amygdala in Mediating Stress Hormone Effects on Memory Consolidation<BR>Role of Emotional Arousal-Induced Noradrenergic Activation Within the Amygdala in Enabling Epinephrine and Glucocorticoid Effects on Memory Consolidation<BR>Conclusions<BR><BR>NEURO-IMMUNE ASSOCIATIVE LEARNING, G. Pacheco-López, M.-B. Niemi, H. Engler, and M. Schedlowski.<BR>Abstract<BR>Introduction<BR>Phenomenon: The Association Between Exteroceptive and Immune Stimuli <BR>Theoretical Framework for Neuro-Immune Associative Learning<BR>Neurobiology of Neuro-Immune Associative Learning<BR>Biological Relevance of Neuro-Immune Associative Learning <BR>Clinical relevance of neuro-immune associative learning<BR>Summary and future perspective<BR>References<BR><BR>HUMAN BRAIN IMAGING STUDIES OF EMOTIONAL MEMORY: UNCOVERING INFLUENCES OF SEX AND HEMISPHERE, L. Cahill<BR>Abstract<BR>Introduction<BR>The Amygdala-- Built to Modulate<BR>Human Subject Studies Relating Amygdala Activity to Emotional Memory<BR>An Aside on Sex Differences in the Brain <BR>Sex-Related Influences on the Amygdala Relation to Memory for Emotional Events <BR>Sex Difference in Human Amygdala Functional Connectivity at Rest<BR>Potential Relationship of the Sex-Related Amygdala Hemispheric Specialization to Hemispheric Global/Local Processing Bias<BR>Some Implications for Disease States<BR>Summary

Reviews the research on the neurobiology of memory. This book shows how cell circuitry is modulated and modified by neurotransmitters and hormones during the process of acquiring, consolidating, and retrieving information. It also addresses memory studies involving human brain imaging.