part, 1 Introduction -- chapter 1 Microscale Testing in Aquatic Toxicology: Introduction, Historical Perspective, and Context / Christian Blaise Peter G. Wells Kenneth Lee -- part, 2 Microscale Testing at Various Biological and Phylogenetic Levels -- Biochemical Assays -- chapter 2 Immunoassays: Applications for the Aquatic Environment / Andrea Dankwardt Sabine Pullen Bertold Hock -- chapter 3 Environmental Applications with Submitochondrial Particles / Harry W. Read John M. Harkin Karl E. Gustavson -- chapter 4 Bioassays to Measure MFO Inducers in Effluents / Peter V. Hodson Jim Sherry Joanne Parrott -- chapter 5 Enzyme Inhibition for Examination of Toxic Effects in Aquatic Systems / U. Obst A. Wessler M. Wiegand-Rosinus -- part, 1_1 Tissue Culture Assays -- chapter 6 Sponge Cells and Tissue as Biological Monitors of Aquatic Pollution / Werner E.G. Müller Isabel M. Müller -- chapter 7 The Use of Fish Cells in the Toxicological Evaluation of Environmental Contaminants / Francine Denizeau -- chapter 8 In Vitro Assays for Detection of Nongenotoxic Carcinogens / M. J. Durand V. Cruciani S. Alexandre J. C. Hoflack H. Bessi C. Blaise P. Vasseur -- part, 1_2 Bacteria -- chapter 9 Microbial Enzyme Assays for the Detection of Heavy Metal Toxicity / Gabriel Bitton Jean Louis Morel -- chapter 10 ATP-TOX System - A Review / H. Howard Xu -- chapter 11 Luminescent Bacterial Biosensors for the Rapid Detection of Toxicants / Scott F. Briscoe Jie Cai Michael S. DuBow -- chapter 12 Stress-Responsive Luminous Bacteria for Toxicity and Genotoxicity Monitoring / Shimshon Belkin -- chapter 13 Microtox * Toxicity Test Systems - Where They Stand Today / Ansar A. Qureshi Anthony A. Bulich Don L. Isenberg -- chapter 14 Microtox® Toxicity Test System - New Developments and Applications / B. Thomas Johnson -- chapter 15 Measurement of Microbial Exoenzyme Activity in Sediments for Environmental Impact Assessment / K. Lee K.L. Tay -- chapter 16 Small-Scale In Vitro Genotoxicity Tests for Bacteria and Invertebrates / P.-D. Hansen A. Herbert -- part, 1_4 Algae and Microalgae -- chapter 17 Recent Advances in Toxicity Test Methods Using Kelp Gametophytes / B.S. Anderson J.W. Hunt W. Piekarski -- chapter 18 Microplate Toxicity Tests with Microalgae: A Review / Christian Blaise Jean-François Férard Paule Vasseur -- chapter 19 Ecophysiological Considerations in Microalgal Toxicity Tests / C. Nalewajko M.M. Olaveson -- chapter 20 Development and First Validation of a "Stock-Culture Free" Algal Microbiotest:The Algaltoxkit / G. Persoone -- part, 2_5 Protozoa -- chapter 21 Ciliated Protozoa as Test Organisms in Toxicity Assessments / Guy L. Gilron Denis H. Lynn -- chapter 22 Development of a Protozoan Chemoattraction Inhibition Assay for Evaluating Toxicity of Aquatic Pollutants / Sharon G. Berk Robert O. Roberts -- chapter 23 Ciliate Microbiotest Applications: Metal Contaminants in Water and Soil / James R. Pratt Daria G. Mochan Nancy J. Bowers -- part, 2_6 Invertebrates -- chapter 24 Utility and Practical Considerations for In Vitro Developmental Toxicity Testing: Hydra and FETAX Assays / E. Marshall Johnson -- chapter 25 Microscale Bioassays for Corals / M. Branton -- chapter 26 The Use of Larvae and Small Species of Polychaetes in Marine Toxicological Testing / Donald J. Reish -- chapter 27 Development of a Canadian Marine Toxicity Test for Whole Sediments Using Cultured Spionid Polychaetes / Patricia Pocklington Kenneth G. Doe -- chapter 28 Microscale Toxicity Testing With Rotifers / Terry W. Snell Colin R. Janssen -- chapter 29 Recent Advances in Microscale Toxicity Testing with Marine Mollusks / John W. Hunt Brian S. Anderson Bryn M. Phillips -- chapter 30 Development and Validation of Toxkit Microbiotests with Invertebrates, in Particular Crustaceans / G. Persoone -- chapter 31 Death by Mud: Amphipod Sediment Toxicity Tests / Peter M. Chapman -- chapter 32 Physiological Dysfunction in Estuarine Mysids and Larval Decapods with Chronic Pesticide Exposure / Charles L. McKenney -- part, 2_7 Teleosts and Amphibians -- chapter 33 Aquatic Testing with Early Life Stages of Killifish / Judith S. Weis Peddrick Weis -- chapter 34 Genotoxicity in Fish Embryos / Armin Herbert Peter-Diedrich Hansen -- chapter 35 Genotoxicity Tests in Amphibians - A Review / V. Ferrier L. Gauthier C. Zoll-Moreux J. L'Haridon -- part, 2_8 Multitrophic Assessment in Practice -- chapter 36 Marine and Estuarine Porewater Toxicity Testing / R. Scott Carr -- chapter 37 Correspondence of a Microscale Toxicity Test to Responses to Toxicants in Natural Systems / John Cairns B. R. Niederlehner Eric P. Smith -- chapter 38 Role of Microbiotests in Contaminated Sediment Assessment Batteries / Philippe Ross -- part, 3 Validation, Applications, and Training with Microscale Testing -- chapter 39 The Influence of Particle Size, Ammonia, and Sulfide on Toxicity of Dredged Materials for Ocean Disposal / K. L. Tay K. G. Doe A. J. MacDonald K. Lee -- chapter 40 Oil Spill Treating Agents: Present Knowledge and Toxicity Testing Needs / Alan J. Mearns -- chapter 41 The Development, Validation, and Analysis of Salmonella Mutagenicity Test Methods for Environmental Situations / Larry D. Claxton -- chapter 42 Investigating the Sources and Fate of Genotoxic Substances in Aquatic Ecosystems with the SOS Chromotest / Paul A. White Chantale Côté -- chapter 43 The Development and Application of Sediment Toxicity Tests for Regulatory Purposes / Marion G. Nipper -- part, 4 Conclusions and Future Directions -- chapter 44 Microscale Testing in Aquatic Toxicology: Conclusions and Future Directions / Kenneth Lee Peter G. Wells Christian Blaise.

Bioassays are among the ecotoxicologist's most effective weapons in the evaluation of water quality and the assessment of ecological impacts of effluents, chemicals, discharges, and emissions on the aquatic environment. Information on these assessment aids is needed throughout the international scientific and environmental management community. This comprehensive reference provides an excellent overview of the small-scale aquatic bioassay techniques and applications currently in use around the world.This special volume is the result of several years of collaboration between Environment Canada and Fisheries and Oceans Canada. Internationally recognized research scientists at many institutions have contributed to this state-of-the-art examination of the exciting, environmentally important field of microscale testing in aquatic toxicology.Microscale Testing in Aquatic Toxicology contains over forty chapters covering relevant principles, new techniques and recent advancements, and applications in scientific research, environmental management, academia, and the private sector.